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2024 Impact Factor of CJCR: 6.3
Journal Citation Reports ™, Clarivate Analytics

Temporal trends, disease burden and attributable risk factors of stomach and colorectal cancers among 31 countries and territories in Western Pacific region, 2000−2021

Stomach cancer (SC) and colorectal cancer (CRC) present significant public health challenges because of their high incidence and mortality. According to the International Agency for Research on Cancer (IARC), more than 968,000 new cases and nearly 660,000 deaths of SC occurred in 2022, ranking the cancer as fifth in terms of both incidence and mortality worldwide. Among the six WHO regions, the Western Pacific region (WPR) suffered from the heaviest burdens of SC and CRC.

Global, regional, and national burden of colorectal cancer, 1990−2021: An analysis from global burden of disease study 2021

Data on the global, regional and national changes in the trends of colorectal cancer (CRC) are analyzed to understand the trends in its burden, in order to assist policymakers in allocating healthcare resources and developing prevention and control strategies. Referring to the latest data from the GBD 2021, this study quantifies the impact of different factors on the global, regional, and national burden of disease associated with CRC, and focuses on the differences in the burden of CRC across different SDI regions as well as across different age groups. This study was conducted to rationally allocate medical resources and optimize preventive strategies based on the analysis of the results.

Artificial intelligence efficiently predicts gastric lesions, Helicobacter pylori infection and lymph node metastasis upon endoscopic images

Artificial intelligence has been widely applied in analysis of medical images, including computed tomography images, endoscopic images, histological images, and organoids images. In the current research, the performance of 14 convolutional neural network models was explored for classification and prediction of endoscopic images from human stomach. The purpose is to improve diagnostic accuracy and working efficiency. By training and comparison, EfficientNetB7 revealed the best performance on two-category of gastric cancer and benign lesions, gastric ulcer and ulcerated cancer, as well as early gastric cancer and non-gastric cancer. The EfficientNetB7 was also suitable for predicting the infection of Helicobacter pylori (Hp) and non-Hp infection (noHp). Notable, the InceptionV3 model was capable of predicting perigastric lymph nodes metastasis from endoscopic images.

IMpower210: A phase III study of second-line atezolizumab vs. docetaxel in East Asian patients with non-small cell lung cancer

Non-small cell lung cancer (NSCLC) accounts for more than 80% of all lung cancers, with most patients presenting with advanced or metastatic disease. Lung cancer incidence is particularly high among Asians, who constitute approximately 50% of the global cases. This study reports the results from the phase III IMpower210 study, which compared the efficacy and safety of atezolizumab monotherapy with those of docetaxel in East Asian patients with advanced or metastatic NSCLC who had experienced disease progression with platinum-based chemotherapy. IMpower210 did not meet its primary efficacy endpoint of OS in the ITT EGFR-WT or overall ITT populations. Atezolizumab was comparatively more tolerable than docetaxel, with a lower incidence of grade 3/4 TRAEs.

Plant-based dietary patterns and risk of esophageal cancer: A prospective cohort study spanning 17 years

Plant-based diets have multiple health benefits for cancers; however, little is known about the association between plant-based dietary patterns and esophageal cancer (EC). This study presents an investigation of the prospective associations among three predefined indices of plant-based dietary patterns and the risk of EC. It performed endoscopic screening for 15,709 participants aged 40−69 years from two high-risk areas of China from January 2005 to December 2009 and followed the cohort until December 31, 2022. This study proves that a healthy plant-based dietary pattern was associated with a reduced risk of EC. Emphasizing the healthiness and quality of plant-based diets may be important for preventing the development of EC.

National Health Commission guidelines for diagnosis and treatment of colorectal cancer 2023 in China (English version)

National Health Commission of the People’s Republic of China; Society of Oncology, Chinese Medical Association

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Vol 37, No 6 (Dec 2025)

Special Issue on Cancer burden in China: Epidemiology, etiology, and prevention

Preface

Preface to Special Issue: Cancer burden in China: Epidemiology, etiology, and prevention

Jiafu Ji

Pages: 879-881 HTML

Review Article

Epidemiology, early detection, and management of breast cancer in China: A comprehensive review

Hangcheng Xu, Binghe Xu

Pages: 882-899 HTML

Leukemia epidemiology in China: Burden, trends, and determinants in the 21st century

Lijuan Hu, Yi Xia, Xiaojun Huang

Pages: 900-911 HTML

Cancer statistics in China: Epidemiology, risk factors, and prevention

Wei Cao, Kang Qin, Bingyang Liu, Wanqing Chen

Pages: 912-928 HTML

Evolving diagnostic and surveillance strategies in esophageal cancer screening: Evidence from population-based studies in China

Zhonghu He, Yang Ke

Pages: 929-936 HTML

Gastric cancer in China: Epidemiology, risk factors, and screening

Yuxin Wang, Zongchao Liu, Wenqing Li, Yang Zhang, Kaifeng Pan

Pages: 937-948 HTML

NHCPRC Guidelines

National Health Commission guidelines for diagnosis and treatment of colorectal cancer in China (2025 edition, English version)

Department of Medical Administration, National Health Commission of the People’s Republic of China; Chinese Medical Association Oncology Branch

Pages: 949-961 HTML

Original Article

Factors associated with neoadjuvant therapy insensitivity and its prognostic impact in HER2-positive breast cancer

Yuhang Han, Bo Lan, Zexi Peng, Yueran Jia, Danyang Ji, Xinzhu Tian, Yuanting Yang, Die Sang, Xuemin Xue, Jiayu Wang, Fei Ma, Yang Luo, Pin Zhang, Binghe Xu, Ying Fan

Pages: 962-972 HTML

Diagnostic sensitivity of mammography and magnetic resonance imaging for ductal carcinoma in situ in high-risk breast cancer screening: A systematic-review and meta-analysis

Mengmeng Li, Yixuan Lin, Keris Poelhekken, Marcel J.W. Greuter, Geertruida H. de Bock, Monique D. Dorrius

Pages: 973-983 HTML

A multicenter study of a predictive model for pathological complete response after neoadjuvant therapy in breast cancer using multimodal digital biomarkers

Zixuan Yang, Jie He, Taolang Li, Changdong Liu, Yongsheng Wang, Yu Ren, Wenhe Zhao, Choo Chiap Chiau, Qiang Li, Liang Xu, Jian Yue, Ting Liang, Lidan Jin, Xiaoyu Fang, Bohui Shi, Zhiqiang Shi, Peng Yuan, Michael Gnant

Pages: 984-999 HTML

Metabolic reprogramming signature predicts immunotherapy efficacy in lung adenocarcinoma: Targeting SLC25A1 to overcome immune resistance

Pengpeng Zhang, Xiaoqing Liang, Bicheng Ye, Xiaofei Wang, Yijie Wang, Zetian Gong, Yuming Huang, Jinyang Liu, Chenjun Huang, Peng Luo

Pages: 1000-1019 HTML

Development and validation of a clinical risk-prediction model for immune checkpoint inhibitor-related pneumonitis in patients with gastrointestinal cancer based on four machine learning algorithms

Yixuan Wang, Liyan Zhang, Zhenzhen Su, Xuemin Lian, Zhihao Lu

Pages: 1020-1033 HTML

Curcumol overcomes cisplatin resistance and rewires glycolysis-H3K9la-ORC6 axis to trigger ferroptosis in bladder cancer

Facai Zhang, Yunkai Yang, Rong Zhang, Huan Hu, Chuanzan Zhou, Jie Wang, Ruicheng Wu, Enhui Li, William C. Cho, Dahong Zhang, Qi Zhang, Dechao Feng

Pages: 1034-1057 HTML

Commentary

Hematology specialist nurse-led continuity-of-care for high-risk hematopoietic cell transplantation recipients

Ting Wang, Li Wu, Aiyun Jin, Xiaming Zhu, Wenjun Xie, Yun Fang, Yanyan Chai, Songhua Luan, Xin Du, Michelle Kenyon, Xia Yan

Pages: 1058-1061 HTML

Corrigendum

Corrigendum to Discovery and validation of indole nitroolefins as novel covalent GPX4 inhibitors for inducing ferroptosis in urological cancers

Pages: 1062 HTML

NHCPRC Guidelines

National Health Commission guidelines for diagnosis and treatment of colorectal cancer in China (2025 edition, English version)

Department of Medical Administration, National Health Commission of the People’s Republic of China; Chinese Medical Association Oncology Branch

Pages: 949-961 HTML

National Health Commission guidelines for diagnosis and treatment of colorectal cancer 2023 in China (English version)

National Health Commission of the People’s Republic of China; Society of Oncology, Chinese Medical Association

Pages: 197-232 HTML