Article Abstract

Expression of Gli1 in the hedgehog signaling pathway and breast cancer recurrence

Authors: Naoko Takebe,Sally Hunsberger,Sherry X. Yang

Abstract

The hedgehog (Hh) signaling pathway plays an essential role in the embryonic development and homeostasis of diverse adult tissues, and its deregulation has been implicated in the tumorigenesis and metastasis of various malignancies including breast cancer.