Article Abstract

EXPRESSION OF BLOOD AFPmRNA IN THE PATIENTS WITH DISTANT METASTASIS OF HUMAN HEPATOCELLULAR CARCINOMA (HCC)

Authors: Yang Liu,Guangxiang Qian,Baihe Zhang,Han Chen,Mengchao Wu

Abstract

Objective: To study blood AFPmRNA expression in patients with distant metastasis of human hepatoceilular carcinoma (HCC).

Methods: Using nested reverse transcriptase polymerase chain reaction (nested RTPCR) to detect 93 blood samples from human HCC cases.

Results: AFPmRNA was detected in 21 blood samples from 72 human HCC (40.28%) without distant metastasis, all HCC patients with distant metastasis were detected with AFPmRNA (100%).

Conclusions: AFPmRNA can be used as a distant metastasis marker of HCC.

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