Article Abstract

INTERNAL DRAINAGE COMBINED WITH INTRAOPERATIVE RADIOTHERAPY AND CHEMOTHERAPY FOR PANCREATIC HEAD CARCINOMA

Authors: Yu Duan,Yue-wei Wang,Huan-zhou Xue

Abstract

Abstract: To improve the palliative effect on intermediate or advanced pancreatic head carcinoma.

Methods: Operations were performed in 26 patients with intermediated or advanced pancreatic head carcinoma. Cholecystojejunostomy or choledochojejunostomy combined with intraoperative radiotherapy with an electron beam on carcinoma were performed from May, 1996 to May, 1998. Meanwhile the catheter of multifunctional implantable drug delivery system was inserted via gastroduodenal artery for postoperative perfusion chemotherapy.

Result: The 3-27 month follow-up survey suggested that the tumors shrank in different degrees after the course of treatment. All patients were relieved of pain. The 6-month, 12-month and 24-month survival rates were 100%, 93.9% and 20% respectively. The average survival time of the 5 dead patients was 17.8 months.

Conclusion: This operation is very effect to prolong the life of the patients with intermediate or advanced pancreatic head carcinoma.

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